The Houston Astros have now had three starting pitchers land on the injured list in two weeks, with Hunter Brown and Cristian Javier both out with Grade 2 shoulder strains and Cody Bolton exit with back tightness, underscoring rotation depth concerns.

Tatsuya Imai and Jeremy Peña were placed on the injured list amid a seven-game skid, with Imai dealing with arm fatigue and Peña a Grade 1 hamstring strain and no clear return timetable.

Houston’s internal rotation options are stretched, featuring Brown, Javier, Burrows, Imai, Lance McCullers Jr., and others such as Ronel Blanco (Tommy John), Bolton (back tightness), Spencer Arrighetti, Jason Alexander, and Hayden Wesneski (Tommy John) as depth pieces.

Houston is allowing an MLB-worst 6.31 runs per game this season, well above the next-worst team, the Nationals at 5.87, highlighting ongoing mound and defensive struggles.

The injuries and losing streak have slashed postseason odds, with FanGraphs cutting playoff chances from 32.8% to 26.4% and division odds from 12.0% to 9.2%, as Houston sits 6-10 and last in the AL West.

Peña’s injury history includes a World Baseball Classic finger issue before a hamstring strain, which has prompted the team to move Carlos Correa to shortstop and Isaac Paredes to third to cover infield gaps.

Peña’s early-season numbers stand at .256/.304/.349 over 16 games, and his absence could shift infield duties, with Correa likely taking short and Paredes handling third.