The solution includes 35 specialty-specific large language model chats that can connect to electronic health records to guide individualized patient care.

The system is built as an augmentative copilot, not an autonomous prescriber, preserving clinician judgment.

The chat tool is updated daily with emerging clinical trial results, guideline updates, and new drug safety warnings, alongside established clinical pathways.

Gelareh Zadeh, M.D., Ph.D., emphasizes that the CDS supports clinicians without replacing professional judgment.

The tool aims to reduce cognitive overload by embedding curated knowledge directly into the EHR, minimizing the need to leave the EHR for external resources.

The CDS includes 22 clinical calculators accessible by chat or voice dictation, offering Mayo Clinic-developed proprietary calculators and standard industry tools for decision support.

A suite of 22 voice- and text-enabled calculators provides risk and diagnostic calculations using standard and Mayo Clinic-developed algorithms.

There are 22 calculators that deliver medical information and evidence-based decision support on demand.

Mayo Clinic Platform has launched an AI-enabled Clinical Decision Support (CDS) that injects Mayo Clinic knowledge and evidence-informed guidance directly into clinicians’ workflows.

Leadership says the CDS is continually evaluated with physician feedback to align with Mayo Clinic’s patient-care approach.

The CDS is designed to reduce time clinicians spend searching multiple resources, freeing more time for patient care, with plans to expand as more tools are added to the Platform.

Subspecialty-Specific Clinical Chat covers 35+ specialties, uses an integrated large language model to assist with natural-language queries, and automatically cites peer-reviewed literature.