A University of Leeds study reports older male endurance athletes face increased risks of heart scarring and abnormal rhythms, particularly in the left ventricle. Despite exercise's benefits, the findings stress monitoring heart health among veteran athletes, with further research planned to include women.

Australian researchers unveil CoVEXS5, a new COVID-19 vaccine offering broad protection against multiple variants, including Omicron XBB.1.5. Developed with a unique spike protein, CoVEXS5 has shown to reduce virus levels in mice by 99.9%, and includes an open-access adjuvant to promote global vaccine equity.

A study reveals telemedicine visits in 2021 led to a 2.4% lower imaging rate compared to in-person visits, suggesting it doesn't increase healthcare overuse. Researchers urge further investigation into the appropriateness of imaging orders during telemedicine consults.

Cantargia's TRIFOUR trial of nadunolimab shows promising early results in treating advanced triple-negative breast cancer, but Phase 2 did not significantly improve response rates over chemotherapy alone. Despite this, the drug was well-tolerated, and further analyses are awaited to assess its potential benefits.

Cancer stem cells are pivotal in tumor recurrence and resistance to therapy, necessitating targeted strategies. Research emphasizes understanding CSC-immune interactions to improve treatment effectiveness.

UC San Diego researchers are advancing our understanding of life's origins by creating synthetic cells that mimic metabolism. This pioneering work, detailed in Nature Chemistry, could revolutionize fields from drug delivery to environmental science within two decades.

Researchers at Texas A&M AgriLife have created 'nanoflowers,' innovative nanoparticles that promote mitochondrial health and protect brain cells. Published in The Journal of Biological Chemistry, these nanoparticles show promise in addressing neurodegenerative diseases by targeting oxidative stress and improving neuronal integrity.

A new study reveals that human eggs maintain viability over decades by slowing internal waste disposal, reducing metabolic activity to minimize damage. This strategy, crucial for preserving egg quality, suggests that a natural low-metabolism state could be more beneficial than metabolic supplements.

Researchers at the S. N. Bose Centre have innovated a sustainable method to produce hydrogen peroxide using just water and sunlight. This photocatalytic breakthrough could transform industries by offering a cost-effective and eco-friendly alternative to conventional production methods.

A study in The American Journal of Clinical Nutrition shows eggs don't raise LDL cholesterol when part of a low saturated fat diet, challenging past beliefs about their impact on heart health. The research suggests saturated fats, not dietary cholesterol, are the main concern, urging a reevaluation of eggs as a dietary option.

PARP1 inhibitors, like talazoparib, show promise against EBV-driven lymphomas by disrupting cancer growth without causing DNA damage, a study in the Journal of Medical Virology finds. This approach could expedite treatment for aggressive cancers, with research extending to other EBV-related malignancies.

Researchers have engineered gut bacteria to combat kidney stones by absorbing oxalates, showing promising results in animal and human trials. While the innovation holds potential for treating hyperoxaluria, challenges like limited efficacy and biosafety concerns remain.

Researchers are pioneering a dual mRNA vaccine combining 5T4 and CD70 mRNA-LNPs to enhance immune responses against prostate cancer. This strategy shows promise in boosting tumor suppression and extending survival in preclinical models, addressing a critical need for advanced therapies.

Gut microbes influence colorectal cancer by altering the tumor suppressor gene p53's function. Bacteria like E. coli can promote cancer, but gut metabolites may stabilize p53, affecting cancer treatment strategies.

New research identifies PHGDH, traditionally a metabolic enzyme, as a key RNA-binding protein stabilizing PRKCD mRNA, thus promoting mitophagy in liver cancer cells. Targeting PHGDH in mouse models reduced tumor growth, presenting a novel therapeutic avenue for hepatocellular carcinoma.

New research reveals middle-aged individuals with heart disease and diabetes face heightened dementia risks, especially when compounded by strokes and mental health issues. Published in Brain Communications, the study emphasizes understanding health patterns and timing to develop effective prevention strategies, with experts advising lifestyle changes to mitigate risk.

A JAMA Oncology study reveals COVID-19 vaccine boosters dramatically reduce hospitalizations in cancer patients, yet uptake remains low. Despite their efficacy, only 38% received the bivalent booster.

Eight babies in the UK have been born using a groundbreaking three-person IVF technique to prevent mitochondrial diseases. This pioneering method, legal only in the UK, replaces defective mitochondria and offers hope to families at genetic risk.

Dennis Assanis has been appointed as the new chancellor of UC Santa Barbara, starting September 1, 2025, succeeding Henry Yang. His tenure at the University of Delaware was marked by significant research growth and innovation.