OpenAI Foundation launches a $40 million data-grant program through Data for Public Health to build high-quality scientific datasets that advance AI in medicine, starting with cancer vaccines and a platform called OpenAdmet for drug-effect prediction.

The effort aims to improve tumor antigen selection and vaccine formulations to accelerate development and clinical use of personalized cancer vaccines, beginning with trials in triple-negative breast cancer.

Researchers Benjamin Vincent and Alex Rubinsteyn will assemble and analyze de-identified tumor and immune-cell data from three biobanks to train AI models that identify better antigens and guide vaccine design.

1Day Sooner has secured datasets from two disclosures and is pursuing more, highlighting the competitive and contentious landscape for acquiring proprietary data from bankruptcies.

A core strategy is to obtain common technical documents from bankrupt entities, including regulatory correspondence, manufacturing methods, and safety data, to give AI deep real-world insights into drug development and regulation.

OpenADMET seeks to slash drug development failures by using data to predict pharmacokinetics, drawing on precedents like AI models trained with large biological datasets.

CTD Commons will reduce duplication and costs in clinical research by providing open access to comprehensive drug development records, covering toxicology, manufacturing, and FDA correspondence.

Teslo argues the drug development regulatory process is a black box and that more data is essential to turn AI from theory into practical breakthroughs.

Teslo proposed using bankruptcy filings from failed biotech companies as a data resource, calling it biotech’s lost archive, with a $500,000 grant to 1Day Sooner to pursue this approach.

Scientific data are framed as essential for research, with potential breakthroughs when AI models access broad, high-quality datasets.

The program invites ongoing collaboration and outlines next steps, including updates as science progresses and opportunities to contribute via [email protected].

Media contact for UNC Health is Kendall Rovinsky; the release includes background on UNC Lineberger and the OpenAI Foundation.