Heart failure mortality rates in the U.S. have increased by 3% since 1999, reversing prior declines.

Younger Americans are experiencing a disproportionate rise in heart failure deaths, with a ninefold increase under age 45 and fourfold in the 45-64 age group.

Obesity and diabetes, as comorbidities, are significant factors in the rising trend of heart failure, especially among younger populations.

The COVID-19 pandemic has exacerbated heart failure mortality rates, both directly and by straining healthcare resources and exacerbating disparities.

The study highlights an urgent need for new research and strategies in prevention and treatment to combat the growing heart failure mortality rate.