Arc Institute Teams Up with Genomics Leaders to Revolutionize Virtual Cell Atlas Development

April 28, 2025
Arc Institute Teams Up with Genomics Leaders to Revolutionize Virtual Cell Atlas Development
  • Gilad Almogy, CEO of Ultima Genomics, noted that the complexity of cells presents both challenges and opportunities for understanding biological systems.

  • This initiative aims to transition the Atlas from observational to perturbational data, which is crucial for training machine learning models to predict cellular responses.

  • Launched two months ago, the Arc Virtual Cell Atlas features over 300 million cells and focuses on generating high-quality datasets to inform virtual cell models and other scientific innovations.

  • Serge Saxonov, CEO of 10x Genomics, highlighted the innovative potential of building a virtual cell, which could revolutionize scientific research and accelerate drug development.

  • The vision for the virtual cell includes interactive visualization and manipulation of cellular states, potentially transforming our understanding of cell biology.

  • Patrick Hsu, co-founder of Arc, advocates for predictive models of cellular responses to improve therapeutic targeting, moving away from traditional experimental methods.

  • Overall, this collaborative project aims to unite academia, industry, and technology to drive significant advancements in scientific research.

  • The Arc Institute has partnered with 10x Genomics and Ultima Genomics to enhance the development of the Arc Virtual Cell Atlas, which seeks to create large-scale datasets of cell states for scientific research.

  • Additionally, 10x Genomics will provide its Chromium Flex technology, enabling researchers to analyze millions of perturbed cells simultaneously, facilitating the exploration of complex biological questions.

  • To support this effort, Ultima Genomics will utilize its UG 100 sequencing system and Solaris chemistry, designed to produce higher quality data at lower costs.

  • The collaboration leverages advanced technologies from both 10x and Ultima to enhance data collection processes, making them faster, more detailed, and cost-effective.

  • Positioned as an open-source resource, the Arc Virtual Cell Atlas aims to standardize and minimize inconsistencies in single-cell data, making it accessible for broader scientific use.

Summary based on 3 sources


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