Breakthrough Chimeras Target Folate Receptors to Degrade Cancer Proteins

June 13, 2025
Breakthrough Chimeras Target Folate Receptors to Degrade Cancer Proteins
  • Among the significant papers cited are those focusing on lysosome-targeting chimeras and their applications in cancer, along with the effectiveness of bispecific aptamer chimeras for protein degradation.

  • The study references various important works that explore targeted protein degradation mechanisms, advancements in cancer treatment, and the crucial role of folate receptors in cancer biology.

  • Recent research has unveiled the development of polyvalent folate receptor-targeting chimeras designed to effectively degrade membrane proteins.

  • This innovative approach highlights the significant potential of chimeras in the realm of targeted protein degradation, particularly within cancer therapy.

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