Hyperbaric Oxygen Therapy Reverses Biological Aging, Lengthens Telomeres in New Study
August 23, 2025
Experts suggest that HBOT could serve as a cost-effective alternative to pharmaceutical aging treatments, although the need for daily sessions may present practical challenges.
The study involved 35 healthy adults aged 64 and older who underwent 60 daily oxygen therapy sessions over three months, leading to increased telomere length and reduced senescent cells in their blood.
Researchers emphasize that telomere shortening is a critical focus in aging biology, and this therapy offers a new approach to reversing cellular aging at the biological level.
The therapy involves breathing pure oxygen in a pressurized chamber, which induces physiological effects similar to hypoxia—effects previously linked to cognitive improvements—now shown to potentially reverse cellular aging.
A groundbreaking study has demonstrated for the first time that hyperbaric oxygen therapy (HBOT), traditionally used for conditions like decompression sickness and carbon monoxide poisoning, can reverse biological aging in humans.
This study marks a significant advancement in aging research, showing that HBOT can effectively reverse key markers of aging within just three months.
Compared to previous methods such as drugs like danazol or lifestyle changes like exercise and diet, HBOT resulted in much greater effects, particularly in lengthening telomeres over a short period.
The research revealed that telomeres, the DNA sequences at chromosome ends that shorten with age, were significantly lengthened, indicating a reversal of one of the core biological signs of aging.
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Popular Mechanics • Aug 22, 2025
It Sure Looks Like Humans Have Found a Way to Reverse Aging