Breakthrough: Genetically Modified Pig Lung Transplanted into Brain-Dead Human, Survives 9 Days
September 12, 2025
A groundbreaking xenotransplantation has been achieved where a genetically modified pig lung was successfully transplanted into a brain-dead human, surviving nine days, marking a significant advance in organ transplantation technology.
Researchers at Guangzhou Medical University genetically engineered the pig's lung by editing six genes to reduce rejection risk, addressing the major challenge of immune response in cross-species organ transplants.
This success could help alleviate the organ shortage, with 13 patients dying daily in the U.S. while waiting for transplants, and efforts are already underway to transplant genetically modified pig kidneys as well.
The research builds on previous experiments, such as the 2019 revival of a pig brain post-mortem using BrainEx technology, which restored cellular function but did not imply consciousness or life.
Experts like Emil Kendziorra suggest that, although recreating a human brain remains impossible now, future advances in organ engineering and cryopreservation could bring humanity closer to the goal of extending life indefinitely.
This development raises the possibility of using genetically engineered organs to extend human lifespan and potentially achieve a form of biological immortality, especially when combined with advances in brain preservation and revival techniques.
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