The project seeks to understand whether genetic factors contributed to Leonardo's extraordinary creativity and visual acuity, potentially revealing physical traits and vulnerabilities.

By creating a genetic portrait of Leonardo, researchers hope to challenge and expand current understanding of his life, genius, and physical characteristics.

Scientists are nearing the completion of the Leonardo DNA Project, which aims to analyze the DNA of Leonardo da Vinci's living male descendants and ancient remains to uncover his genetic profile.

DNA tests on six of Leonardo's descendants confirmed the continuity of the Y chromosome across at least 15 generations, supporting the authenticity of their lineage.

This ambitious project is a collaboration involving institutions like The Rockefeller University, the University of Florence, and the J. Craig Venter Institute, with support from various foundations.

Genealogical research has traced a family tree of over 400 individuals back to 1331, identifying 15 direct male-line descendants connected to Leonardo's relatives.

Reconstructing Leonardo's DNA is seen as a milestone that bridges science and cultural heritage, offering a deeper understanding of his identity and inspiring pride in Vinci.

Historical and genealogical research into Leonardo's family environment, including properties and his mother Caterina's background, provides context for the genetic study.

The project also explores ideas akin to modern epigenetics, contemplating how factors like diet and parental behavior could influence heredity, reflecting themes central to contemporary genetics.

Scientists are investigating a charcoal drawing called 'Unicorn Dragon' found in Vinci, which may be attributed to Leonardo based on its style and iconography, with plans for scientific analysis.