Cascade Bio’s 'Body Armor for Enzymes' Revolutionizes Industrial Biomanufacturing with Extended Enzyme Lifespan

September 13, 2025
Cascade Bio’s 'Body Armor for Enzymes' Revolutionizes Industrial Biomanufacturing with Extended Enzyme Lifespan
  • Cascade Bio has developed a groundbreaking enzyme stabilization technology called Body Armor for Enzymes, which extends enzyme lifespan from hours to several months by protecting enzymes from degradation using scalable, affordable materials.

  • This technology significantly enhances enzyme stability, allowing enzymes to maintain activity for months under industrial conditions, a major improvement over previous lifespans of only hours.

  • Early collaborations demonstrate that stabilized enzymes can operate for months, greatly improving costs and ease of use in various industrial applications.

  • Based in Denver with operations in California and New York, Cascade Bio has raised $6 million in funding to advance its enzyme-based, cell-free biomanufacturing processes, aiming to replace traditional petrochemical methods.

  • The funding includes a $2.8 million seed round led by Endurance28, along with $3.2 million in nondilutive grants from the U.S. NSF, supporting the company's development efforts.

  • The funding round was participated in by Stray Dog Capital, 1Flourish, Range Ventures, 10VC, and Amplify, highlighting strong investor confidence in Cascade Bio's vision.

  • Founded by Alex Rosay and James Weltz, with backgrounds in chemical engineering and experience at Zymergen, Stanford, and CU Boulder, the company is strategically positioned to lead in industrial biotechnology.

  • Cascade Bio aims to be a leader in enzyme immobilization technology, with a mission to make chemical production faster, cleaner, and more sustainable.

  • Investors, including Endurance28, praise the company's scientific rigor and ambitious vision, positioning it as a key player in the biomanufacturing revolution.

  • The company's platform has successfully stabilized over thirty different enzymes, increasing their durability and enabling integration into sectors like chemicals, pharmaceuticals, and food manufacturing.

  • Cascade Bio has collaborated with more than 20 industrial customers, achieving a 100% success rate in improving enzyme stability across various applications.

  • CEO Alex Rosay emphasizes that their technology can extend enzyme activity from hours to months, promising a transformative impact on biocatalysis costs and usability.

Summary based on 2 sources


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