Aging, especially in individuals aged 65 and older, significantly increases vulnerability to health issues, particularly cardiometabolic diseases.

Poor lifestyle choices, including unhealthy diets and low physical activity, exacerbate the incidence of chronic diseases among the elderly.

Cellular senescence, marked by DNA damage and oxidative stress, is a major contributor to aging-related diseases, including metabolic syndrome and cardiovascular diseases.

Curcumin, an active compound in turmeric, shows promise in alleviating symptoms and diseases associated with aging due to its antioxidant and anti-inflammatory properties.

This compound mitigates oxidative stress by scavenging free radicals and activating cellular defense mechanisms, which may benefit metabolic functions.

Curcumin also positively influences metabolic functions, helping to lower blood glucose levels and improve vascular function, thereby reducing blood pressure.

A systematic review collected 2,737 articles and identified seven randomized controlled trials that focused on curcumin's effects on elderly populations with cardiometabolic diseases.

The results from these studies indicated that curcumin significantly reduces inflammatory biomarkers like C-reactive protein and interleukin-6, particularly in older adults.

These findings support further exploration of curcumin as an adjunctive therapy for managing age-related inflammatory and degenerative diseases, especially in the context of metabolic syndrome and cardiovascular diseases.

However, the review acknowledges limitations due to heterogeneity among the included studies regarding design, population, and intervention protocols.