L'Oréal has launched its Longevity Integrative Science initiative in Paris, aiming to address the root biological causes of skin aging rather than focusing solely on surface-level cosmetic corrections.

This initiative recognizes the skin's crucial role in overall health, targeting factors such as DNA damage, mitochondrial function, and inflammatory signaling to combat the aging process.

To enhance preventive and regenerative skin health, the initiative employs advanced diagnostics, biotechnology, and proprietary AI.

L'Oréal's collaborations with Swiss biotech Timeline and UK biotech SENISCA are pivotal, focusing on rejuvenating aged mitochondria and developing senotherapeutics for age-related diseases.

Additionally, a partnership with TruDiagnostic is focused on understanding gene expression changes over time to create long-term solutions for skin and hair vitality.

L'Oréal collaborates with experts like Andrea Maier and Rob Knight to explore the connections between skin health and systemic health, including the microbiome and neurodegenerative diseases.

Barbara Lavernos, L'Oréal's head of research, envisions a future where beauty and longevity are interconnected, promoting vibrant and healthy aging.

Central to this effort is L'Oréal's 'Wheel of Longevity for Beauty,' which decodes the mechanisms of skin aging at cellular, molecular, and tissular levels.

The Longevity AI Cloud is a key component, analyzing over 260 skin biomarkers and mapping 32 biological pathways to detect changes in skin health, allowing for precise intervention strategies.

SENISCA's technology aims to reprogram aged senescent cells, which could have significant benefits for skin health and the treatment of age-related conditions.