Dr. David Furman Revolutionizes Aging Research with Inflammation Clock and Longevity Insights
July 7, 2025
Dr. David Furman, a prominent geroscientist originally from Argentina, initially aspired to be a physician but shifted his focus to biology and immunology, driven by a desire to significantly impact public health.
He is known for his research on 'inflammaging,' a term he coined to describe the chronic low-grade inflammation associated with aging, which contributes to various age-related diseases.
Furman's work highlights inflammation as a critical factor in diseases such as cancer and cardiovascular conditions, revealing that inflammatory markers can predict health outcomes in older adults.
He advocates for lifestyle modifications to manage inflammation, sharing personal experiences of moving to a more natural environment and adjusting dietary habits to minimize inflammation triggers.
Furman emphasizes the importance of early intervention in aging-related diseases, aiming for 'molecular interception' by identifying molecular changes before they become clinically observable.
To aid in this effort, he has developed the 'inflammation aging clock' (iAge), which employs a neural network to predict an individual's inflammatory age based on immune protein data.
His research suggests that centenarians have a uniquely low inflammatory age, indicating that understanding their immune profiles could lead to strategies for reducing inflammation and extending healthspan.
At Stanford University, Furman led the Thousand Immunomes project, utilizing a multi-omics approach to study the immune system and its relationship with aging and longevity.
Currently, he is commercializing the iAge clock through his company, Edifice Health, aiming to bridge the gap between research findings and practical health applications.
Summary based on 1 source
Get a daily email with more Science stories
Source

Lifespan Extension Advocacy Foundation • Jul 7, 2025
Dr. David Furman on Inflammation and Aging