Dr. David Furman Revolutionizes Aging Research with Inflammation Clock and Longevity Insights

July 7, 2025
Dr. David Furman Revolutionizes Aging Research with Inflammation Clock and Longevity Insights
  • Dr. David Furman, a prominent geroscientist originally from Argentina, initially aspired to be a physician but shifted his focus to biology and immunology, driven by a desire to significantly impact public health.

  • He is known for his research on 'inflammaging,' a term he coined to describe the chronic low-grade inflammation associated with aging, which contributes to various age-related diseases.

  • Furman's work highlights inflammation as a critical factor in diseases such as cancer and cardiovascular conditions, revealing that inflammatory markers can predict health outcomes in older adults.

  • He advocates for lifestyle modifications to manage inflammation, sharing personal experiences of moving to a more natural environment and adjusting dietary habits to minimize inflammation triggers.

  • Furman emphasizes the importance of early intervention in aging-related diseases, aiming for 'molecular interception' by identifying molecular changes before they become clinically observable.

  • To aid in this effort, he has developed the 'inflammation aging clock' (iAge), which employs a neural network to predict an individual's inflammatory age based on immune protein data.

  • His research suggests that centenarians have a uniquely low inflammatory age, indicating that understanding their immune profiles could lead to strategies for reducing inflammation and extending healthspan.

  • At Stanford University, Furman led the Thousand Immunomes project, utilizing a multi-omics approach to study the immune system and its relationship with aging and longevity.

  • Currently, he is commercializing the iAge clock through his company, Edifice Health, aiming to bridge the gap between research findings and practical health applications.

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Dr. David Furman on Inflammation and Aging

Lifespan Extension Advocacy Foundation • Jul 7, 2025

Dr. David Furman on Inflammation and Aging

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