New Genetic Clue to Left-Handedness Found in TUBB4B Gene Study
April 3, 2024
A study in Nature Communications found a genetic link to left-handedness, particularly in protein-altering variants of the TUBB4B gene.
Left-handed individuals are 2.7 times more likely to carry these rare genetic variants.
The research, involving over 350,000 British adults' genetic data, suggests hand dominance may be influenced by genetics.
The Max Planck Institute for Psycholinguistics team identified a variant associated with tubulin protein production, related to microtubule creation, which differs in left-handed people.
The study implies that this genetic difference may affect cellular chirality and brain hemisphere dominance, influencing hand preference.
However, the precise mechanism connecting tubulin protein variants to left-handedness remains to be fully understood.
Summary based on 6 sources
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Sources

ZME Science • Apr 2, 2024
Researchers find rare genetic variants linked to left-handedness
AOL • Apr 2, 2024
Gene involved in cell shape offers clues on left-handedness
Newsmax • Apr 2, 2024
Study Finds Gene Variant Involved in Left-Handedness