A recent randomized controlled trial published in the Annals of Internal Medicine has shown that adults with metabolic syndrome can significantly improve their A1c levels, weight, and body fat through time-restricted eating (TRE).

Known as the TIMET study, this research is notable for being the first to assess the effects of TRE in patients who are on medication for metabolic syndrome.

Participants in the study adhered to an 8- to 10-hour eating window over a 12-week period, logging their eating habits using the myCircadianClock app.

The fasting group reported an average daily calorie reduction of 350 calories, primarily by consuming fewer carbohydrates and fats, while maintaining stable protein intake.

Key findings revealed a significant positive impact on glycemic control and cardiometabolic health, supporting TRE as an effective lifestyle intervention.

After three months, participants practicing TRE showed marked improvements in blood sugar regulation, cholesterol levels, and body fat, all without losing lean muscle mass.

Those in the TRE group experienced greater reductions in fat mass and hemoglobin A1C levels compared to participants who received only standard dietary guidance.

The study found that TRE was safe for participants, including those on common medications like Metformin and Statins, and offered benefits across various aspects of metabolic syndrome.

Unlike pharmaceuticals, which can have side effects, TRE is a simple, sustainable lifestyle change that allows individuals to maintain their usual diet while altering when they eat.

Funded by the National Institutes of Health and other organizations, the TIMET trial adds to the growing evidence supporting time-restricted eating as a viable health intervention.

Researchers, including co-author Satchidananda Panda, emphasized the need for further research with larger participant groups and longer durations to fully understand the health impacts of TRE.

The findings align with previous studies indicating that TRE and intermittent fasting can effectively aid in weight loss and improve metabolic health, highlighting the urgent need for accessible lifestyle interventions.