New Study Offers Hope for Adult Peanut Allergy Desensitization, But Caution Advised

April 24, 2025
New Study Offers Hope for Adult Peanut Allergy Desensitization, But Caution Advised
  • Public Health Minister Ashley Dalton highlighted the significance of this research, stating it could transform the lives of those with peanut allergies in the UK and potentially worldwide.

  • Personal accounts from participants, such as Chris Lassiter, illustrate the severe impact of peanut allergies on daily life, including multiple hospitalizations due to allergic reactions.

  • Recent research published in the journal Allergy has shown promising results in desensitizing adults with peanut allergies, with 18 participants involved in the study.

  • This study is particularly significant as previous desensitization treatments primarily focused on children, leaving adults without similar options until now.

  • However, researchers noted that not all participants were successfully desensitized, indicating the need for larger trials to better understand the variability in reactions.

  • Experts stress that medical supervision is essential when administering oral immunotherapy, as individuals should not attempt to self-treat.

  • Peanut allergies affect approximately one in 200 adults and one in 50 children, with many individuals continuing to suffer from these allergies into adulthood.

  • Despite the success in desensitization, participants are still considered allergic and must continue to avoid exceeding their daily dose and carry an EpiPen for emergencies.

  • By the end of the trial, two-thirds of these adults were able to consume the equivalent of five peanuts without experiencing allergic reactions.

  • Chief investigator Stephen Till emphasized the importance of further research to confirm these results and cautioned that treatment should only be administered under close medical supervision.

  • Dr. Joao Pedro Matias Lopes also warned that this treatment is not a cure, and maintaining tolerance may require lifelong adherence to peanut consumption.

  • Blood tests from the study indicated increased levels of IgG antibodies post-treatment, which could counteract the allergy-causing IgE antibodies.

Summary based on 19 sources


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Man hospitalised by peanut allergy now eats nuts daily

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