The study highlights alarming disparities in health risks associated with phthalates, particularly in rapidly industrializing regions where plastic consumption is rising and regulatory controls are limited.

Future research aims to track the impact of reduced phthalate exposure on global mortality rates and explore other health concerns related to these chemicals.

A new study published in the journal EBioMedicine estimates that daily exposure to phthalates, chemicals commonly used in plastic production, was linked to over 356,000 deaths from heart disease globally in 2018.

Di-2-ethylhexyl phthalate (DEHP) was identified as a significant contributor to heart disease, responsible for more than 13% of heart disease mortality among individuals aged 55 to 64.

The economic burden of these deaths is estimated to be between $510 billion and $3.74 trillion, underscoring the serious financial impact of phthalate exposure.

While the American Chemistry Council did not comment on the findings, they continue to promote the benefits of certain phthalates, despite growing health concerns.

Dr. Leonardo Trasande, the study's senior author, noted critical disparities in health impacts due to plastic pollution, challenging the notion that these issues primarily affect high-income countries.

Experts recommend practical measures to minimize exposure to phthalates, such as using glass or stainless steel containers and avoiding microwaving plastics.

The researchers utilized health and environmental data from numerous surveys across 200 countries, including urine samples that revealed chemical breakdown products from DEHP exposure.

The research, conducted by NYU Langone Health, revealed that regions such as the Middle East, South Asia, East Asia, and the Pacific accounted for approximately 75% of these heart disease fatalities.

Researchers emphasize the urgent need for global regulations to limit exposure to phthalates, especially in areas with increased plastic production and consumption.

Scientists are advocating for better monitoring of chemical additives in plastics, as many countries lack disclosure requirements, leading to higher risks in low-income nations.