Prenatal 'Forever Chemicals' Linked to Higher Teen Blood Pressure, Study Finds
June 13, 2025
Research published in the Journal of the American Heart Association reveals that prenatal exposure to per- and polyfluoroalkyl substances (PFAS), commonly referred to as 'forever chemicals,' can lead to increased blood pressure in teenagers.
The study, which followed 1,094 children from the Boston Birth Cohort over 12 years, found that boys and children born to non-Hispanic Black mothers experienced a more significant rise in blood pressure linked to PFAS exposure.
Specifically, boys exposed to PFDeA showed a 9% higher risk of developing high blood pressure between the ages of 6 and 12, and a 17% higher risk during their teenage years.
PFAS are synthetic compounds used in various consumer products for their water and grease resistance, and exposure primarily occurs through drinking water, food, and household items.
These chemicals accumulate in the environment and human bodies over time, raising concerns about long-term health effects.
Lead author Mingyu Zhang noted that boys may absorb these environmental toxins more effectively due to slower elimination rates, resulting in higher chemical buildups.
Zhang emphasized the importance of addressing early-life blood pressure patterns, as they can significantly predict future health issues such as heart disease and stroke.
The study highlights the need for further research into the long-term health impacts of prenatal PFAS exposure, particularly as children transition into adolescence.
The authors advocate for stronger environmental regulations and policies to limit PFAS exposure in consumer products and improve water safety.
Interestingly, the study found that certain PFAS were associated with lower diastolic blood pressure in early childhood, although this effect diminished or reversed as the children aged.
However, the study faced limitations, including reliance on a single maternal blood sample taken shortly after delivery and fewer blood pressure measurements during adolescence compared to childhood.
The Boston Birth Cohort included a diverse population, with 61% of participants identifying as non-Hispanic Black, 22% as Hispanic, and 17% from other racial and ethnic backgrounds.
Summary based on 2 sources
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Sources

ABC News • Jun 12, 2025
Exposure to 'forever chemicals' before birth linked to higher blood pressure in kids
Medical Xpress • Jun 12, 2025
Exposure to 'forever chemicals' before birth may raise blood pressure during teen years, research suggests