Prenatal 'Forever Chemicals' Linked to Higher Teen Blood Pressure, Study Finds

June 13, 2025
Prenatal 'Forever Chemicals' Linked to Higher Teen Blood Pressure, Study Finds
  • Research published in the Journal of the American Heart Association reveals that prenatal exposure to per- and polyfluoroalkyl substances (PFAS), commonly referred to as 'forever chemicals,' can lead to increased blood pressure in teenagers.

  • The study, which followed 1,094 children from the Boston Birth Cohort over 12 years, found that boys and children born to non-Hispanic Black mothers experienced a more significant rise in blood pressure linked to PFAS exposure.

  • Specifically, boys exposed to PFDeA showed a 9% higher risk of developing high blood pressure between the ages of 6 and 12, and a 17% higher risk during their teenage years.

  • PFAS are synthetic compounds used in various consumer products for their water and grease resistance, and exposure primarily occurs through drinking water, food, and household items.

  • These chemicals accumulate in the environment and human bodies over time, raising concerns about long-term health effects.

  • Lead author Mingyu Zhang noted that boys may absorb these environmental toxins more effectively due to slower elimination rates, resulting in higher chemical buildups.

  • Zhang emphasized the importance of addressing early-life blood pressure patterns, as they can significantly predict future health issues such as heart disease and stroke.

  • The study highlights the need for further research into the long-term health impacts of prenatal PFAS exposure, particularly as children transition into adolescence.

  • The authors advocate for stronger environmental regulations and policies to limit PFAS exposure in consumer products and improve water safety.

  • Interestingly, the study found that certain PFAS were associated with lower diastolic blood pressure in early childhood, although this effect diminished or reversed as the children aged.

  • However, the study faced limitations, including reliance on a single maternal blood sample taken shortly after delivery and fewer blood pressure measurements during adolescence compared to childhood.

  • The Boston Birth Cohort included a diverse population, with 61% of participants identifying as non-Hispanic Black, 22% as Hispanic, and 17% from other racial and ethnic backgrounds.

Summary based on 2 sources


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