Rising Cannabis Potency Linked to Surge in Schizophrenia Risk, Study Finds

August 11, 2025
Rising Cannabis Potency Linked to Surge in Schizophrenia Risk, Study Finds
  • Over the past two decades, cannabis potency has surged in Canada, with tetrahydrocannabinol (THC) concentrations rising from approximately 4% to 20% in most legal dried cannabis.

  • Dr. Nicholas Fabiano, a researcher from the University of Ottawa, highlights that this increase in cannabis potency is likely contributing to a stronger link between cannabis use and schizophrenia.

  • Regular use of high-potency cannabis is particularly concerning, as it is associated with a greater risk of developing psychosis, especially among younger males and those with a history of mental health disorders.

  • A significant study involving nearly 9.8 million people in Ontario found that individuals visiting emergency departments for cannabis use face a staggering 14.3-fold increased risk of schizophrenia-spectrum disorders, with those experiencing cannabis-induced psychosis at a 241.6-fold increased risk.

  • Treatment for cannabis-induced psychosis typically involves stopping cannabis use, and in severe cases, may require antipsychotic medication to manage prolonged symptoms.

  • Behavioral interventions, such as motivational interviewing and cognitive behavioral therapy, can be effective in helping individuals overcome cannabis cravings and adhere to treatment plans.

  • The heightened risk of psychosis associated with high-potency cannabis use is particularly pronounced among frequent users, younger individuals, and males.

Summary based on 2 sources


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