Chronic Pain Linked to Depression: Study Urges Mental Health Support in Pain Management
May 20, 2025
A recent study published in eClinicalMedicine analyzed 21 years of data from over 7,300 adults aged 50 and older in England, focusing on the mental health impacts of chronic pain.
Among the participants, half experienced chronic pain from conditions such as back, knee, hip, or foot issues, while the other half did not suffer from any pain.
The study found that individuals with chronic pain reported heightened levels of depression and loneliness, even years before their pain began.
In contrast, those without pain exhibited fewer and less severe depressive symptoms, which remained stable over time.
Chronic pain affects up to 40% of the population in the UK and Europe, highlighting its significance as a public health concern and a leading cause of disability.
Notably, participants with lower education and wealth levels experienced a more significant increase in depressive symptoms, indicating a need for targeted support for these vulnerable populations.
The authors advocate for integrating mental health support into pain management strategies, particularly for older adults and those with fewer socioeconomic resources.
While the study noted limited differences in social isolation between the pain and non-pain groups, it suggested that the quality of relationships may be more crucial in alleviating pain and depression than the quantity of social interactions.
The research team accounted for various factors influencing results, including demographics, health conditions, and lifestyle choices, ensuring robustness in their findings.
However, the study faced limitations, including a lack of racial and ethnic diversity among participants and the inability to differentiate between general and chronic pain in the survey data.
Future studies are recommended to explore these patterns in younger and more diverse populations, as well as to confirm the findings regarding chronic pain specifically.
Additionally, three-quarters of participants in the pain group reported pain in specific areas, suggesting that future research should include more diverse demographic groups for broader applicability of findings.
Summary based on 5 sources
Get a daily email with more Science stories
Sources

Medical Xpress • May 20, 2025
Depression linked to physical pain years later
Express & Star • May 19, 2025
New study sheds light on pain and depression
The Independent • May 19, 2025
New study finds unexpected link between physical pain and depression - NewsBreak
Surrey Live • May 20, 2025
Chronic condition 40% get signalled years in advance by symptom