New Study Debunks Myth of Taurine Decline with Age, Questions Its Role as Aging Biomarker
June 5, 2025
A new study published today challenges the long-held belief that taurine, an amino acid associated with anti-aging, consistently decreases with age.
Conducted by scientists at the National Institutes of Health, the research analyzed taurine levels in diverse populations, including over 740 participants from the Baltimore Longitudinal Study of Aging, as well as rhesus monkeys and mice.
The study, which involved blood analysis from participants aged 26 to 100, found that taurine levels actually increased with age in most cohorts, except for male mice.
Co-author Maria Emilia Fernandez noted that a decline in taurine is not universally associated with aging, indicating that taurine may not be a reliable biomarker for aging.
Despite these findings, taurine remains significant for health, and low levels could still contribute to chronic health issues in some older individuals.
Gerontologist Rafael de Cabo stated that taurine supplementation is unnecessary for those maintaining a healthy diet, reinforcing the study's conclusions.
A clinical trial is currently underway to explore whether taurine supplements can enhance health in middle-aged adults, led by Vijay Yadav, with results anticipated by late 2025.
Researchers continue to advocate for further studies on taurine's potential health benefits, with ongoing clinical trials examining its effects on aging in humans.
While effective strategies for healthy aging, such as regular exercise, are established, the quest for a definitive anti-aging supplement like taurine remains uncertain.
Experts, including David Sinclair from Harvard University, find the study's longitudinal approach more convincing than previous cross-sectional studies, which often lead to misinterpretations.
De Cabo's research utilized a longitudinal method, analyzing the same individuals over time, contrasting with earlier studies that gathered data from different age groups at a single point.
Taurine plays various roles in the body, including aiding digestion and serving as an antioxidant, though its concentrations can vary based on medical conditions such as obesity and cancer.
Summary based on 3 sources
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Sources

Nature • Jun 5, 2025
Anti-ageing effects of popular supplement taurine challenged
Gizmodo • Jun 5, 2025
Taurine Might Not Be the Anti-Aging Miracle We Hoped For