Researchers describe resilience as a developable skill, aiming to bolster long-term well-being for survivors through standardized coping tools within two years post-treatment.

The piece outlines a paradigm shift toward collaborative, preventative, and personalized cancer care, integrating molecular genetics, survivorship psychology, environmental health, and interdisciplinary infrastructure to accelerate discovery and improve patient outcomes.

In February 2026, Genes & Development published a study, alongside ongoing projects like the SMART 3RP Lymphoma Study and the Grand opening of the Kenneth C. Griffin Cancer Research Building, with long-term results anticipated from multidisciplinary work this year.

There is a shift toward patient-centered research, prioritizing patient-reported outcomes alongside clinical results, exemplified by Dr. Frank Penedo’s trial enrolling 250 patients to teach coping strategies.

Dr. Shria Kumar leads GI oncology work focused on prevention—eradicating Helicobacter pylori and addressing early-onset colon cancer—while highlighting disparities and the need for targeted screening.

Sylvester Comprehensive Cancer Center reports a breakthrough in chemotherapy resistance by blocking a regulatory protein, which induces transcriptional stress and restores chemo sensitivity in resistant cancer cells, as detailed in Genes & Development.

The research highlights transcriptional stress as a mechanism to sensitize cancer cells to DNA-damaging chemotherapy, advancing synthetic lethality and precision oncology.

The Genes & Development publication explains that inhibiting specific proteins removes cellular brakes, triggering transcriptional stress and making cancer cells more vulnerable to chemotherapy, illustrating synthetic lethality.

The SMART 3RP Lymphoma Study assesses survivorship and resilience, offering survivors a standardized toolkit to improve long-term quality of life within two years post-treatment, emphasizing behavioral medicine as a core component.

The Griffin Building is designed to break down research silos through real-time data sharing and robotic screening, positioning Miami as a global hub for medical research and related tourism.

The GI oncology effort under Dr. Kumar emphasizes prevention and disparities, including Helicobacter pylori eradication to prevent stomach cancer and targeted screening for early-onset colon cancer.

The Kenneth C. Griffin Cancer Research Building opens as an integrated, open-concept 12-story facility designed to speed bench-to-bedside translation by housing researchers, clinicians, and wellness spaces in close proximity, fostering ‘research neighborhoods’ and real-time data sharing.