The 12th annual Breakthrough Prize ceremony, held in Santa Monica, blended science recognition with a star-studded red carpet, underscoring the event as a high-profile philanthropic celebration of scientific achievement.

A-list attendance highlighted the spectacle, with guests including Anne Hathaway, Ben Affleck, Jessica Chastain, Bill Gates, Chrissy Teigen, John Legend, Michelle Yeoh, Olivia Wilde, Robert Downey Jr., Zoe Saldana and many more.

The Breakthrough Prize honors breakthroughs in science and is described as a prestigious philanthropic event that publicly celebrates scientific progress.

Frank Merle was named the mathematics winner at the ceremony.

Michelle Williams chose a simple, sleek black gown with carefully selected jewelry for subtle sparkle on the red carpet.

Rock climber Alex Honnold voiced hope that political changes are temporary, while scientific knowledge continues to grow in the long term.

David J. Gross was recognized as a Special Breakthrough Prize in Fundamental Physics recipient.

Awardees in life sciences contributed to gene therapies for inherited blindness, sickle cell disease, and beta-thalassemia, and identified genetic causes for ALS and frontotemporal dementia.

The ceremony featured six prizes of $3 million each, plus six New Horizons Prizes of $100,000 for early-career researchers, and three Maryam Mirzakhani New Frontiers Prizes of $50,000 for women PhD graduates.

Winners hailed from top institutions such as UC Berkeley, Stanford, Princeton, University of Pennsylvania, MIT, Caltech, Oxford, and Duke.

Lily Collins wore a strapless olive column gown with a polished, timeless silhouette.

Gigi Hadid stood out in a white halter-neck gown with a statement brooch for a modern red-carpet look.