Global Consortium Unveils Groundbreaking Brain-Spine Neural Connectivity Study in Nature
June 8, 2026
A large-scale, data-driven neuroscience study on neuronal connectivity and network organization across a brain-spine/cord connectome is driven by a consortium (BANC-FlyWIRE) and extensive data resources.
The author list spans multiple institutions worldwide, with several authors sharing equal contributions (Bates, Phelps, Kim, Yang).
The paper appears in Nature, published on June 8, 2026, with a DOI indicating formal publication.
Titled Distributed control circuits across a brain-and-cord connectome, the study maps neural circuits that span the brain and nervous system within a connectome framework.
Supplementary Information is extensive, including neuron metadata across datasets such as FAFB, MANC, and maleCNS, and analyses like PCA-UMAP, spectral clustering, and functional annotations.
The supplementary material details cross-dataset neuron metadata alignment, UMAP embeddings, clustering analyses, and data-quality artifacts' bounding boxes, signaling a thorough cross-dataset approach to neuron types and connectivity.
Corresponding authors hail from Harvard Medical School and related institutions, underscoring a broad, multi-institutional collaboration.
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Nature • Jun 8, 2026
Distributed control circuits across a brain-and-cord connectome