Ancient Mutation Behind Blue Eyes Traced to Single Ancestor 6,000-10,000 Years Ago
June 21, 2026
While this switch explains most inherited blue eyes, other genetic pathways can produce pale eyes, indicating more factors beyond the single switch.
DNA evidence shows blue-eyed populations from diverse regions carry the same genetic signature around the switch, pointing to a common origin.
From this ancient mutation, hundreds of millions of blue-eyed individuals share a single origin encoded in their DNA.
Estimates are based on genetic inference rather than birth records, and ordinary blue eyes are the most common inherited form, not all light-eye conditions.
A tiny switch in the HERC2 gene controls the neighboring OCA2 gene, reducing iris pigment to produce blue eyes.
Eye color is controlled by multiple genes, but a specific mutation acts as the primary on-off switch for the common blue-eye trait, limiting pigment in the iris.
The mutation is believed to have emerged in Neolithic Europe or the Near East, though the exact origin and timing remain uncertain.
Blue-eyed people around the world are likely descendants of a single founder who lived roughly 6,000 to 10,000 years ago.
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