Abridge, a startup specializing in automating doctors' note-taking through artificial intelligence, has successfully raised $300 million in a Series E funding round led by Andreessen Horowitz, boosting its valuation to $5.3 billion.

This significant funding will be allocated towards hiring scientists, machine-learning experts, and software developers to enhance product development and strengthen AI infrastructure.

Abridge's technology is currently utilized in over 150 large health systems across the United States, marking a 50% increase in usage compared to four months ago, and it is projected to support more than 50 million medical conversations this year.

The startup's innovative ambient-listening technology records and transcribes conversations between doctors and patients, significantly reducing the time physicians spend on administrative tasks and helping to alleviate clinician burnout.

Notable health systems, including Johns Hopkins Medicine and Mayo Clinic, are implementing Abridge's technology, highlighting a growing interest in ambient AI solutions for healthcare documentation.

Dr. Shiv Rao, Abridge's CEO, emphasizes the company's commitment to alleviating clerical burdens for clinicians through innovative AI applications across various care settings.

In a competitive market, Abridge and similar startups like Nabla and CodaMetrix are expanding their offerings to enhance their value proposition to healthcare customers.

Rao noted the rapid adoption of generative AI solutions in healthcare, which is outpacing other industries, driven by the increasing availability of large language model technology.

Funding for AI and healthcare startups reached $7.5 billion in 2024, with 2025 already on track to surpass this figure, having seen $5.6 billion invested by late June.

This latest funding round follows a previous $250 million raise announced in February 2025, contributing to a total of around $800 million raised since Abridge's inception seven years ago.

Abridge's efforts also include a focus on pediatric care documentation and partnerships to integrate additional resources, such as UpToDate from Wolters Kluwer Health, into their AI platform.

Advancements in AI are also influencing clinical research, particularly through the use of digital twins to streamline drug trials and reduce costs and timelines.