The fire caused multiple roof and wall collapses, prompting efforts to shield nearby businesses and properties from spreading fire.

The incident remains ongoing, and officials say updates will follow as containment efforts continue.

A massive factory fire in Greenacre, Sydney, involving a timber flooring and furniture factory, broke out around 3:00 pm on Tuesday and is expected to burn for a considerable time.

About 60 firefighters and 20 fire appliances were deployed to battle the blaze as crews worked to prevent spread and manage structural collapses.

The building is well alight, with bricks and walls collapsing in parts as authorities fight the flames.

Firefighters gained access to several buildings to extinguish flames and ensure everyone is accounted for, with no injuries reported so far.

An exclusion zone has been established and motorists are urged to avoid the area.

NSW Police have also reinforced the exclusion area to keep residents away from the scene.

There are no reported injuries at this stage, and investigators are probing the cause of the blaze, urging the public to share any footage or information.

Authorities have not yet determined a cause, and are appealing for information or footage from the public as part of the investigation.

Officials believe everyone is accounted for as crews continue to secure the scene.

The fire is expected to burn for a considerable time, with ongoing containment efforts and further updates anticipated.