Study: 40% of Chronic Pain Patients Face Depression and Anxiety, Urging Integrated Care Solutions
March 10, 2025
Despite historical links between chronic pain and mood disorders, the severity of co-occurrence found in this study underscores the necessity for routine mental health screenings in clinical settings.
Younger adults and women were identified as being more likely to suffer from depression and anxiety related to chronic pain, emphasizing the need for targeted interventions.
Conducted by researchers at Johns Hopkins University, the systematic review analyzed data from 376 studies involving 347,468 individuals across 50 countries, providing a comprehensive look at the mental health challenges associated with chronic pain.
The findings indicate that individuals with fibromyalgia are particularly vulnerable, with over half showing signs of both depression and anxiety, while the prevalence of these symptoms varies by pain condition.
The research emphasizes the importance of addressing mental health in patients with chronic pain to enhance overall health outcomes and suggests that innovative treatments tailored to this demographic are necessary.
Dr. Rachel Aaron, who led the study, stressed the need for integrated treatments that address both chronic pain and mental health, as current therapies often treat these issues separately.
While many individuals with chronic pain do not experience depression or anxiety, the significant rates among certain groups challenge the assumption that chronic pain is inherently linked to mental distress.
This study highlights a pressing need for healthcare providers to routinely screen for mental health issues among patients suffering from chronic pain, in order to better address this public health concern.
Understanding the interplay between chronic pain and mental health is crucial, as individuals with mood disorders may be dismissed as having psychosomatic issues and could be excluded from clinical trials.
A recent study published in JAMA Network Open reveals that approximately 40% of adults suffering from chronic pain also experience clinically significant symptoms of depression or anxiety, highlighting a critical public health issue.
Specifically, the study found that depression rates were highest in fibromyalgia patients at 54.0 percent, followed by anxiety at 55.5 percent, whereas arthritis conditions reported lower rates of 29.1 percent for depression and 17.5 percent for anxiety.
Summary based on 3 sources
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Sources

ScienceDaily • Mar 10, 2025
Worldwide study finds high rates of depression and anxiety in people with chronic pain
STAT • Mar 10, 2025
Chronic pain linked with depression, anxiety
Medical Xpress • Mar 10, 2025
Study: 4 in 10 adults with chronic pain report depression, anxiety