Study Links 356,000 Heart Disease Deaths to Phthalates, Calls for Global Plastic Regulation

April 29, 2025
Study Links 356,000 Heart Disease Deaths to Phthalates, Calls for Global Plastic Regulation
  • A recent study led by NYU Langone Health estimates that daily exposure to phthalates, chemicals commonly used in plastic production, was linked to over 356,000 deaths from heart disease globally in 2018.

  • The research highlights that regions such as the Middle East, South Asia, East Asia, and the Pacific accounted for approximately 75% of these heart disease-related deaths.

  • The International Agency for Research on Cancer classifies DEHP as 'possibly carcinogenic' to humans, although its cancer-causing effects are primarily observed in rodents.

  • The economic burden of deaths linked to DEHP exposure is estimated between $10.2 billion and $3.74 trillion, factoring in lost productivity and healthcare costs.

  • Addressing DEHP exposure will require coordinated actions across supply chains, improved waste management, and stronger regulations to protect vulnerable populations.

  • Dr. Leonardo Trasande, the study's senior author, noted alarming disparities in health impacts due to plastic pollution, challenging the notion that these issues are confined to high-income countries.

  • The study identified di-2-ethylhexyl phthalate (DEHP) as a significant contributor, responsible for more than 13% of heart disease mortality among individuals aged 55 to 64.

  • Researchers emphasize the urgent need for global regulations to mitigate phthalate exposure, particularly in rapidly industrializing regions with high plastic consumption.

  • To reduce exposure, experts recommend minimizing the use of plastics, avoiding microwaving plastic containers, and opting for natural storage materials like glass and stainless steel.

  • Barrett calls for urgent action to reduce phthalate exposure and plastic consumption worldwide, framing the study's findings as a wake-up call for public health.

  • The observational nature of the research indicates correlation rather than causation, underscoring the need for more direct, long-term studies to understand the health impacts of phthalate exposure.

  • Scientists are advocating for better monitoring of chemical additives in plastics, as many countries do not require disclosure of these substances, which often end up in low-income nations.

Summary based on 15 sources


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