Colorectal cancer has become the leading cancer killer among Americans under 50 in 2023, with both death rates and incidence rising in younger adults.

Experts point to missed chances for earlier diagnosis and advocate for reduced stigma, better symptom recognition, and expanded screening, including colonoscopy starting at 45 with 10-year intervals for those at average risk and earlier screening for those with a family history.

Dr. William Dahut notes a 44% decline in cancer deaths among under-50s due to better therapies and reduced smoking, but warns that regular screening and prompt follow-up remain crucial for younger patients.

The Colorectal Cancer Alliance offers resources such as a free helpline, a free screening tool, and a Young-Onset Support community to help patients and families.

This story originated in Men’s Journal on January 22, 2026, with attribution and links to source materials.

There are controversial claims about funding cuts to cancer research and NIH, with reductions and a 2026 budget proposal potentially impacting cancer research resources.

Identified risk factors include processed and fried foods, alcohol, sedentary lifestyle, and early antibiotic exposure, though many patients do not fit these profiles, underscoring ongoing questions about colorectal cancer risk.

Key leaders, including the Colorectal Cancer Alliance’s Michael Sapienza and Chief Medical Consultant John Marshall, emphasize urgency for increased research funding and collaboration.

Efforts should focus on underserved populations and address structural factors that create inequities in cancer prevention, detection, and care.

The JAMA study, drawing on American Cancer Society and medical researchers, discusses implications and possible drivers of the rising trend in young-onset colorectal cancer.

The Alliance provides contact and organizational information, including its Washington, DC headquarters and active social media presence, highlighting its role as the leading national nonprofit for colorectal cancer.

Colonoscopy preparation can be a barrier, requiring a day-long clear-liquid diet and laxatives, though the procedure is described as painless with twilight sedation.